Basic information Safety Supplier Related

(3-PIPERAZIN-1-YL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER

Basic information Safety Supplier Related

(3-PIPERAZIN-1-YL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER Basic information

Product Name:
(3-PIPERAZIN-1-YL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER
Synonyms:
  • 1-(3-N-Boc-propyl)-piperazine
  • tert-Butyl (3-(piperazin-1-yl)propyl)carbaMate
  • 1-(3-Aminoprop-1-yl)piperazine, 1-BOC protected 97%
  • tert-Butyl [3-(piperazin-1-yl)prop-1-yl]carbamate, 1-{3-[(tert-Butoxycarbonyl)amino]prop-1-yl}piperazine
  • 1-(3-N-Boc-aminopropyl)piperazine
  • 1-(3-Boc-aminopropyl)-piperazine, 97%
  • BUTTPARK 90\06-03
  • (3-PIPERAZIN-1-YL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER
CAS:
874831-60-4
MF:
C12H25N3O2
MW:
243.35
Product Categories:
  • pharmacetical
Mol File:
874831-60-4.mol
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(3-PIPERAZIN-1-YL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER Chemical Properties

Boiling point:
372.4±27.0 °C(Predicted)
Density 
1.003±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
12.86±0.46(Predicted)
form 
oil
color 
Colourless to pale yellow
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Safety Information

HS Code 
2933599590
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(3-PIPERAZIN-1-YL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER Usage And Synthesis

Uses

tert-Butyl N-[3-(piperazin-1-yl)propyl]carbamate is a linker that can be used for synthesis of PROTAC degrader TrimTAC1 (HY-169355)[1].

References

[1] Lu P, et al., Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders. Cell. 2024 Oct 30:S0092-8674(24)01197-8. DOI:10.1016/j.cell.2024.10.015

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