Basic information Safety Supplier Related

4,4-DIMETHYL-2-PHENYL-2-OXAZOLINE

Basic information Safety Supplier Related

4,4-DIMETHYL-2-PHENYL-2-OXAZOLINE Basic information

Product Name:
4,4-DIMETHYL-2-PHENYL-2-OXAZOLINE
Synonyms:
  • 4,4-DIMETHYL-2-PHENYL-2-OXAZOLINE
  • 4,4-Dimethyl-2-phenyl-2-oxazoline 96%
  • 4,4-Dimethyl-2-phenyl-4,5-dihydro-1,3-oxazole
  • Oxazole, 4,5-dihydro-4,4-dimethyl-2-phenyl-
CAS:
19312-06-2
MF:
C11H13NO
MW:
175.23
Product Categories:
  • Building Blocks
  • Heterocyclic Building Blocks
  • Oxazolines/Oxazolidines
Mol File:
19312-06-2.mol
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4,4-DIMETHYL-2-PHENYL-2-OXAZOLINE Chemical Properties

Melting point:
20-24 °C(lit.)
Boiling point:
124 °C20 mm Hg(lit.)
Density 
1.025 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.5322(lit.)
Flash point:
217 °F
pka
4.82±0.70(Predicted)
BRN 
132225
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3

MSDS

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4,4-DIMETHYL-2-PHENYL-2-OXAZOLINE Usage And Synthesis

Uses

4,4-Dimethyl-2-phenyl-2-oxazoline may be used in the synthesis of an ester-ammonium salt via rupture of oxazoline ring.

Synthesis Reference(s)

Journal of the American Chemical Society, 82, p. 2032, 1960 DOI: 10.1021/ja01493a045
Tetrahedron Letters, 27, p. 5269, 1986 DOI: 10.1016/S0040-4039(00)85187-4

General Description

4,4-Dimethyl-2-phenyl-2-oxazoline is an 2-aryl-2-oxazoline and has been tested as as ligand for the Suzuki coupling reaction of aryl bromides and arylboronic acids. 4,4-Dimethyl-2-phenyl-2-oxazoline forms mildly hygroscopic complexes, of general formulae [ZnX2(ox)2] (ox =4,4-Dimethyl-2-phenyl-2-oxazoline), with ether solutions of [ZnX2] (X = Cl, Br, I).Except ZnI2, which does not form an isolable complex due to steric reasons.

4,4-DIMETHYL-2-PHENYL-2-OXAZOLINESupplier

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