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FMOC-L-3-BENZOTHIENYLALANINE

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FMOC-L-3-BENZOTHIENYLALANINE Basic information

Product Name:
FMOC-L-3-BENZOTHIENYLALANINE
Synonyms:
  • Fmoc-Beta-(3-Benzothien
  • 3-(1-benzothiophen-3-yl)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]propanoic acid
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl L-3-Benzothienylalanine
  • N-Fmoc-S-(Benzothien-3-yl)-alanine
  • (2S)-3-(1-benzothiophen-3-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
  • (αS)-α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]benzo[b]thiophene-3-propanoic acid
  • N-Fmoc-3-(benzo[b]thiophen-3-yl)-L-alanine
  • 3-(3-Benzothienyl)-N-FMoc-L-alanine, 95%
CAS:
177966-60-8
MF:
C26H21NO4S
MW:
443.52
Product Categories:
  • Phenylalanine analogs and other aromatic alpha amino acids
  • Amino Acid Derivatives
  • a-amino
  • Amino Acids
Mol File:
177966-60-8.mol
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FMOC-L-3-BENZOTHIENYLALANINE Chemical Properties

Boiling point:
690.8±55.0 °C(Predicted)
Density 
1.356±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
form 
Solid
pka
3.74±0.10(Predicted)
color 
White to off-white
optical activity
-43.8° (C=0.01 g/ml, DMF)
InChIKey
BQIZNDWONIMCGM-CRPMJUFNNA-N
SMILES
C(C1C2=CC=CC=C2C2C=CC=CC1=2)OC(=O)N[C@H](C(=O)O)CC1=CSC2C=CC=CC1=2 |&1:18,r|
CAS DataBase Reference
177966-60-8(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Safety Statements 
22-24/25
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2934999090

MSDS

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FMOC-L-3-BENZOTHIENYLALANINE Usage And Synthesis

Chemical Properties

White to off-white powder

Uses

It is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Alanine is one of the simplest amino acids - a methyl group as the side chain. This small side chain confers a high degree of flexibility (second only to glycine) when incorporated into a polypeptide chain. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group.

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