S(+)-NIGULDIPINE HYDROCHLORIDE Chemical Properties

Boiling point:

729.5±60.0 °C(Predicted)

Density 

1.205±0.06 g/cm3(Predicted)

storage temp. 

−20°C

solubility 

DMSO: 13 mg/mL

form 

solid

pka

8.45±0.10(Predicted)

color 

yellow

Safety Information

WGK Germany 

3

S(+)-NIGULDIPINE HYDROCHLORIDE Usage And Synthesis

Uses

S-(+)-Niguldipine Hydrochloride is a calcium channel blocker and α1a-adrenergic antagonist.

Definition

ChEBI: (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid O5-[3-(4,4-diphenyl-1-piperidinyl)propyl] ester O3-methyl ester is a diarylmethane.

Biological Activity

L-type Ca 2+ channel blocker and α 1A -adrenoceptor antagonist; more active enantiomer.

S(+)-NIGULDIPINE HYDROCHLORIDE(113165-32-5)Related Product Information

• Nitrendipine
• S(+)-NIGULDIPINE HYDROCHLORIDE
• 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester
• 3,3-Diphenylpropylamine
• Ethyl 3-(methylamino)-2-butenoate
• N-Methyl-3,3-diphenylpropylamine
• 3-(3-Nitrophenyl)propionic acid
• Ethyl 3-(ethylamino)crotonate
• 1-Piperidinepropanol
• 3-Phenylglutaric acid
• 3-(3-AMINOPHENYL)PROPIONIC ACID
• Methyl 2-benzylacrylate
• 4-(4'-N-METHYLBENZAMIDE)PIPERIDINE
• 2-METHYLENE-PENTANEDIOIC ACID
• 3-(3-NITRO-PHENYL)-PROPIONALDEHYDE
• (-)-Nitrendipine
• 4-N-Methylbenzyl-N-carbethoxypiperidine dihydrochloride
• 3-(DIMETHYLAMINO)PROPYL ACRYLATE