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G418

Basic information Safety Supplier Related

G418 Basic information

Product Name:
G418
Synonyms:
  • O-2-AMINO-2,7-DIDEOXY-DELTA-GLY-CERO-ALPHA-D-GLUCO-HEPTO-PYRANOSYL[1->4]-O-3-DEOXY-4C-METHYL-3-[METHYL-AMINO]-BETA-L-ARABINOPYRONOSYL-DELTA-STREPTAMINE, DISULFATE SALT
  • AMINOGLYCOSIDE ANTIBIOTIC
  • ANTIBIOTIC G418
  • ANTIBIOTIC G418 DISULFATE
  • ANTIBIOTIC G418 DISULFATE SALT
  • GENETICIN DISULFATE
  • GENETICIN DISULFATE SALT
  • GENETICIN(R)
CAS:
49863-47-0
MF:
C20H40N4O10
MW:
496.55
Mol File:
49863-47-0.mol
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G418 Chemical Properties

Melting point:
>193°C (dec.)
Boiling point:
760.3±60.0 °C(Predicted)
Density 
1.47±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
H2O: 50 mg/mL
form 
white powder
pka
13.29±0.70(Predicted)
color 
White to Off-White
Stability:
Hygroscopic
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Safety Information

Hazard Codes 
Xn
Risk Statements 
20/21/22
Safety Statements 
22-24/25
WGK Germany 
3

MSDS

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G418 Usage And Synthesis

Uses

Geneticin Disulfate Salt, is an aminoglycoside antibiotic, structurlly similar to Gentamicin B1. It is produced by Micromonospora rhodorangea. G418 blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.

Definition

ChEBI: An aminoglycoside antibiotic produced by Micromonospora rhodorangea. It blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.

IC 50

Aminoglycoside

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