Aspochalasin M
Aspochalasin M Basic information
- Product Name:
- Aspochalasin M
- Synonyms:
-
- Aspochalasin M
- (3S,3aR,4S,6aS,7E,12S,15aS)-3,3a,4,6a,9,10,13,14-octahydro-12-hydroxy-4,5,8-trimethyl-3-(2-methylpropyl)-1H-cycloundec[d]isoindole-1,11,15(2H,12H)-trione
- 1H-Cycloundec[d]isoindole-1,11,15(2H,12H)-trione, 3,3a,4,6a,9,10,13,14-octahydro-12-hydroxy-4,5,8-trimethyl-3-(2-methylpropyl)-, (3S,3aR,4S,6aS,7E,12S,15aS)-
- CAS:
- 1173040-34-0
- MF:
- C24H35NO4
- MW:
- 401.54
- Mol File:
- 1173040-34-0.mol
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Aspochalasin M Chemical Properties
- Boiling point:
- 617.0±55.0 °C(Predicted)
- Density
- 1.14±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- A solid
- pka
- 12.65±0.70(Predicted)
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Aspochalasin M Usage And Synthesis
Description
Aspochalasin M inhibits the growth of HL-60 cells (IC50 = 20 μM).
Uses
Aspochalasin M is a colorless solid. Aspochalasin M shows modest activity against HL-60 cells with an IC50 of 20.0 μM. Aspochalasin M has the potential for the research of leukemic disease[1].
References
[1] Zhenjian Lin, et al. Spicochalasin A and New Aspochalasins from the Marine-Derived Fungus Spicaria elegans.
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