Pitstop 2
Pitstop 2 Basic information
- Product Name:
- Pitstop 2
- Synonyms:
-
- 1-Naphthalenesulfonamide, N-[5-[(4-bromophenyl)methylene]-4,5-dihydro-4-oxo-2-thiazolyl]-
- Pitstop 2 >=98% (HPLC)
- Inhibitor,vesicle,terminal,endocytosis,domain,synaptic,amphiphysin,clathrin,inhibit,HIV,Pitstop2,Human immunodeficiency virus
- N-[5-[(4-Bromophenyl)methylene]-4,5-dihydro-4-oxo-2-thiazolyl]-1-naphthalenesulfonamide
- N-(5-(4-Bromobenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)naphthalene-1-sulfonamide
- Clathrin-IN-1, 10 mM in DMSO
- CAS:
- 1332879-52-3
- MF:
- C20H13BrN2O3S2
- MW:
- 473.36
- Mol File:
- 1332879-52-3.mol
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Pitstop 2 Chemical Properties
- storage temp.
- -20°C
- solubility
- DMSO: 20 mg/ml
- form
- powder
- color
- white to light brown
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Pitstop 2 Usage And Synthesis
Uses
Pitstop 2 has been used as an inhibitor of clathrin-mediated endocytosis.
Biochem/physiol Actions
Pitstop 2 is a selective inhibitor of clathrin-mediated endocytosis that acts via blocking ligand access to the clathrin terminal domain. Pitstop 2 selectively inhibits clathrin-mediated HIV entry and stalls clathrin-coated pit (CCP) dynamics.
Pitstop 2Supplier
Sigma-Aldrich
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