Basic information Safety Supplier Related

3-Deoxy-1,2-O-isopropylidene-5-p-tuluoyl-beta-L-threo pentofuranose

Basic information Safety Supplier Related

3-Deoxy-1,2-O-isopropylidene-5-p-tuluoyl-beta-L-threo pentofuranose Basic information

Product Name:
3-Deoxy-1,2-O-isopropylidene-5-p-tuluoyl-beta-L-threo pentofuranose
Synonyms:
  • 3-Deoxy-1,2-O-isopropylidene-5-p-tuluoyl-beta-L-threo pentofuranose
  • 3’-Deoxy-1,2-O-isopropylidene-5-O-(p-toluoyl)-L-arabinofuranose
  • 3-Deoxy-1,2-O-isopropylidene-5-O-toluoyl-b-L-ribofuranose
  • 3-Deoxy-1,2-O-isopropylidene-5-p-tuluoyl-b-L-threopentofuranose
CAS:
2072145-19-6
MF:
C16H20O5
MW:
292.33
Mol File:
2072145-19-6.mol
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3-Deoxy-1,2-O-isopropylidene-5-p-tuluoyl-beta-L-threo pentofuranose Chemical Properties

Boiling point:
386.7±27.0 °C(Predicted)
Density 
1.150±0.06 g/cm3(Predicted)
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3-Deoxy-1,2-O-isopropylidene-5-p-tuluoyl-beta-L-threo pentofuranose Usage And Synthesis

Uses

3’-Deoxy-1,2-O-isopropylidene-5-O-(p-toluoyl)-L-arabinofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

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