N1-Cyclopropylmethylpseudouridine
N1-Cyclopropylmethylpseudouridine Basic information
- Product Name:
- N1-Cyclopropylmethylpseudouridine
- Synonyms:
-
- N1-Cyclopropylmethylpseudouridine
- 1-cyclopropylmethylpseudouridine
- 2,4(1H,3H)-Pyrimidinedione, 1-(cyclopropylmethyl)-5-β-D-ribofuranosyl-
- 1-(cyclopropylmethyl)-5-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
- CAS:
- 1613530-18-9
- MF:
- C13H18N2O6
- MW:
- 298.3
- Mol File:
- 1613530-18-9.mol
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N1-Cyclopropylmethylpseudouridine Chemical Properties
- Density
- 1.564±0.06 g/cm3(Predicted)
- pka
- 9.39±0.10(Predicted)
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N1-Cyclopropylmethylpseudouridine Usage And Synthesis
Uses
N1-Cyclopropylmethylpseudouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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