2'-o-methoxyethyl inosine
2'-o-methoxyethyl inosine Basic information
- Product Name:
- 2'-o-methoxyethyl inosine
- Synonyms:
-
- 2'-o-methoxyethyl inosine
- 2'-O-(2-Methoxyethyl) inosine
- Inosine, 2'-O-(2-methoxyethyl)-
- 2'-O-MOE-rI
- 2'-o-methoxyethylinosine
- 2’-O-(2-Methoxy ethyl) inosine
- 9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one
- 9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one
- CAS:
- 545374-76-3
- MF:
- C13H18N4O6
- MW:
- 326.31
- Product Categories:
-
- Nucleosides-2'-O-MOE Nucleosides
- Mol File:
- 545374-76-3.mol
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2'-o-methoxyethyl inosine Chemical Properties
- InChI
- InChI=1S/C13H18N4O6/c1-21-2-3-22-10-9(19)7(4-18)23-13(10)17-6-16-8-11(17)14-5-15-12(8)20/h5-7,9-10,13,18-19H,2-4H2,1H3,(H,14,15,20)/t7-,9-,10-,13-/m1/s1
- InChIKey
- YVCRYUJBJVEBAK-QYVSTXNMSA-N
- SMILES
- OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)O)N=C2)[C@H](OCCOC)[C@@H]1O
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2'-o-methoxyethyl inosine Usage And Synthesis
Uses
2’-O-(2-Methoxyethyl) inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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