Arg-AMS Chemical Properties

Density 

2.00±0.1 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

DMSO : ≥ 100 mg/mL (199.00 mM)

form 

Solid

pka

1.24±0.70(Predicted)

color 

White to off-white

Arg-AMS Usage And Synthesis

Uses

Arg-AMS (compound 24) is a potent nanomolar inhibitor of arginyl tRNA synthetase, which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes[1].

References

[1] Kasai S, et al. Functional profiling of adenylation domains in nonribosomal peptide synthetases by competitive activity-based protein profiling. Chem Commun (Camb). 2015 Nov 11;51(87):15764-7. DOI:10.1039/c5cc04953a