Basic information Safety Supplier Related

PHILANTHOTOXIN 343 TRIS-TRIFLUOROACETATE

Basic information Safety Supplier Related

PHILANTHOTOXIN 343 TRIS-TRIFLUOROACETATE Basic information

Product Name:
PHILANTHOTOXIN 343 TRIS-TRIFLUOROACETATE
Synonyms:
  • N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-Nα-butanoyl-L-tyrosinamide
  • N-[3-[4-(3-Aminopropylamino)butylamino]propyl]-Nα-butyryl-L-tyrosinamide
  • S-N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-4-hydroxy-α-[(1-oxobutyl)amino]-benzenepropanamide tris-trifluoroacetate
  • PHILANTHOTOXIN 343 TRIS-TRIFLUOROACETATE BLOCKS NMDA-GATED ION
  • philanthotoxin 343 tris(trifluoroacetate) salt
  • phtx-343
  • philanthotoxin 343
  • PhTX-343, S-N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-4-hydroxy-α-[(1-oxobutyl)amino]-benzenepropanamide tris-trifluoroacetate
CAS:
115976-93-7
MF:
C23H41N5O3
MW:
435.6
Mol File:
115976-93-7.mol
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PHILANTHOTOXIN 343 TRIS-TRIFLUOROACETATE Chemical Properties

Boiling point:
716.9±60.0 °C(Predicted)
Density 
1.084±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
methanol: >8 mg/mL solutions should be freshly prepared.
form 
solid
pka
9.83±0.15(Predicted)
color 
light yellow-green
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Safety Information

WGK Germany 
3
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PHILANTHOTOXIN 343 TRIS-TRIFLUOROACETATE Usage And Synthesis

Uses

Philanthotoxin 343 tris(trifluoroacetate) salt has been used as Ca2+-permeable α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) blocker. It has also been used as an effective glutamate receptors blocker in an acute homeostasis paradigm to examine the speed of the Neto-α-mediated homeostatic response in Drosophila.

Definition

ChEBI: Philanthotoxin 343 is a N-acyl-amino acid.

Biochem/physiol Actions

Blocks NMDA-gated ion channels; synthetic analog of the wasp polyamine amide toxin δ-philanthotoxin.

PHILANTHOTOXIN 343 TRIS-TRIFLUOROACETATESupplier

Sigma-Aldrich
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021-61415566 800-8193336
Email
orderCN@merckgroup.com
TargetMol Chemicals Inc.
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support@targetmol.com
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PHILANTHOTOXIN 343 TRIS-TRIFLUOROACETATE(115976-93-7)Related Product Information