PHILANTHOTOXIN 343 TRIS-TRIFLUOROACETATE
PHILANTHOTOXIN 343 TRIS-TRIFLUOROACETATE Basic information
- Product Name:
- PHILANTHOTOXIN 343 TRIS-TRIFLUOROACETATE
- Synonyms:
-
- N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-Nα-butanoyl-L-tyrosinamide
- N-[3-[4-(3-Aminopropylamino)butylamino]propyl]-Nα-butyryl-L-tyrosinamide
- S-N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-4-hydroxy-α-[(1-oxobutyl)amino]-benzenepropanamide tris-trifluoroacetate
- PHILANTHOTOXIN 343 TRIS-TRIFLUOROACETATE BLOCKS NMDA-GATED ION
- philanthotoxin 343 tris(trifluoroacetate) salt
- phtx-343
- philanthotoxin 343
- PhTX-343, S-N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-4-hydroxy-α-[(1-oxobutyl)amino]-benzenepropanamide tris-trifluoroacetate
- CAS:
- 115976-93-7
- MF:
- C23H41N5O3
- MW:
- 435.6
- Mol File:
- 115976-93-7.mol
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PHILANTHOTOXIN 343 TRIS-TRIFLUOROACETATE Chemical Properties
- Boiling point:
- 716.9±60.0 °C(Predicted)
- Density
- 1.084±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- methanol: >8 mg/mL solutions should be freshly prepared.
- form
- solid
- pka
- 9.83±0.15(Predicted)
- color
- light yellow-green
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PHILANTHOTOXIN 343 TRIS-TRIFLUOROACETATE Usage And Synthesis
Uses
Philanthotoxin 343 tris(trifluoroacetate) salt has been used as Ca2+-permeable α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) blocker. It has also been used as an effective glutamate receptors blocker in an acute homeostasis paradigm to examine the speed of the Neto-α-mediated homeostatic response in Drosophila.
Definition
ChEBI: Philanthotoxin 343 is a N-acyl-amino acid.
Biochem/physiol Actions
Blocks NMDA-gated ion channels; synthetic analog of the wasp polyamine amide toxin δ-philanthotoxin.