ARPHAMENINE B CAS#: 88465-81-0

ARPHAMENINE B Basic information

Product Name:

ARPHAMENINE B

Synonyms:

5-amino-8-guanidino-2-(4-hydroxyphenylmethyl)-4-oxooctanoicacidhydrochlorid
alpha-(3-amino-6-((aminoiminomethyl)amino)-2-oxohexyl)-4-hydroxybenzenepropa
benzenepropanoicacid,alpha-(3-amino-6-((aminoiminomethyl)amino)-2-oxohexyl)-4
monohydrochloride,(s-(r*,s*))--hydroxy
arphamenine B hydrochloride
Arpharmenine B
Alpha Asarone - crude product

CAS:

88465-81-0

MF:

C16H25ClN4O4

MW:

372.85

EINECS:

207-788-7;226-096-6

Product Categories:

88465-81-0

Mol File:

88465-81-0.mol

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ARPHAMENINE B Usage And Synthesis

Uses

Arphamenine B is a Zn2+-dependent exopeptidase that selectively removes arginine and/or lysine residues from the NH2-terminus of several peptide substrates. Arphamenine B is an inhibitor of aminopeptidase B that can be isolated from bacteria. Arphamenine B enhances the immune response and is used to characterize novel proteases[1][2][3].

References

[1] Foulon T, et al. Aminopeptidase B (EC 3.4.11.6). Int J Biochem Cell Biol. 1999 Jul;31(7):747-50. DOI:10.1016/s1357-2725(99)00021-7
[2] Umezawa H, et al. Arphamenines A and B, new inhibitors of aminopeptidase B, produced by bacteria. J Antibiot (Tokyo). 1983 Nov;36(11):1572-5. DOI:10.7164/antibiotics.36.1572
[3] Kubo H, et al. Involvement of sperm proteases in the binding of sperm to the vitelline envelope in Xenopus laevis. Zoolog Sci. 2008 Jan;25(1):80-7. DOI:10.2108/zsj.25.80

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