AZD-3458
AZD-3458 Basic information
- Product Name:
- AZD-3458
- Synonyms:
-
- AZD-3458
- Acetamide, N-[5-[2-[(1S)-1-cyclopropylethyl]-2,3-dihydro-7-(methylsulfonyl)-1-oxo-1H-isoindol-5-yl]-4-methyl-2-thiazolyl]-
- N-[5-[2-[(1S)-1-cyclopropylethyl]-2,3-dihydro-7-(methylsulfonyl)-1-oxo-1H-isoindol-5-yl]-4-methyl-2-thiazolyl] acetamide
- AZD3458,AZD-3458
- PI3Kγ inhibitor 3
- CAS:
- 2132961-46-5
- MF:
- C20H23N3O4S2
- MW:
- 433.54
- Mol File:
- 2132961-46-5.mol
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AZD-3458 Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- DMSO : 250 mg/mL (576.65 mM; Need ultrasonic)
- form
- Solid
- color
- Off-white to light yellow
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AZD-3458 Usage And Synthesis
Uses
N-[5-[2-[(1S)-1-cyclopropylethyl]-2,3-dihydro-7-(methylsulfonyl)-1-oxo-1H-isoindol-5-yl]-4-methyl-2-thiazolyl] acetamide is used in the preparation of Phosphoinositide 3-Kinase inhibitors.
IC 50
PI3Kγ: 9.1 (pIC50); PI3Kα: 5.1 (pIC50); PI3Kβ: 4.5 (pIC50); PI3Kδ: 6.5 (pIC50); PI3KC2α: 5 (pIC50); PI3KC2β: 7.5 (pIC50); PI3KC2γ: 5.5 (pIC50); PI3KC3: 5.1 (pIC50)
AZD-3458Supplier
Sichuan Wei Keqi Biological Technology Co., Ltd.
- Tel
- 028-81700200 18116577057
- 3003855609@qq.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
- Tel
- 18818260767
- sales@chemegen.com
Bide Pharmatech Ltd.
- Tel
- 400-1647117 13681763483
- product02@bidepharm.com