5’-O-TBDPS-5-methyl-2,2’-anhydrouridine Chemical Properties

Boiling point:

566.0±60.0 °C(Predicted)

Density 

1.26±0.1 g/cm3(Predicted)

pka

12.50±0.60(Predicted)

5’-O-TBDPS-5-methyl-2,2’-anhydrouridine Usage And Synthesis

Uses

5’-O-TBDPS-5-methyl-2,2’-anhydrouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005