(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE
(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE Basic information
- Product Name:
- (2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE
- Synonyms:
-
- L-733,060 HYDROCHLORIDE
- (2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE
- 3-((3,5-Bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine
- L 733060
- Piperidine, 3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenyl-, (2S,3S)-
- L-733,060 hydrochlor
- CAS:
- 148700-85-0
- MF:
- C20H19F6NO
- MW:
- 403.36
- Product Categories:
-
- Tachykinin receptor
- Mol File:
- 148700-85-0.mol
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(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE Chemical Properties
- storage temp.
- 2-8°C
- solubility
- DMSO: >10 mg/mL
- form
- solid
- color
- white
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Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
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(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE Usage And Synthesis
Definition
ChEBI: (2S,3S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine is a member of piperidines.
Biological Activity
A potent antagonist of human tachykinin NK 1 receptors (K i values are 0.08, 0.2 and 93.13 nM for gerbil, human and rat receptors respectively). Produces anxiolytic-like effects in the gerbil elevated plus-maze; orally bioavailable and brain penetrant.
(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDESupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
EMMX Biotechnology LLC
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- 888-539-0666
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Shanghai Universal Biotech Co.,Ltd
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- 18768175414
- gaojun@univ-bio.com