11BETA-HYDROXYTESTOSTERONE Chemical Properties

Melting point:

234.5-235.5 °C

Boiling point:

476.2±45.0 °C(Predicted)

Density 

1.19±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Methanol: Soluble

pka

14.56±0.70(Predicted)

form 

crystalline

color 

light yellow

InChI

InChI=1/C19H28O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-17,21-22H,3-8,10H2,1-2H3/t13-,14-,15-,16-,17+,18-,19-/s3

InChIKey

YQDZGFAYWGWSJK-PUDAZTTPNA-N

SMILES

[C@]12([H])[C@@H](O)C[C@]3(C)[C@H](CC[C@@]3([H])[C@]1([H])CCC1=CC(=O)CC[C@]21C)O |&1:0,2,5,7,10,12,22,r|

Safety Information

Hazard Codes 

Xn,T

Risk Statements 

61-40

Safety Statements 

53-22-36/37/39

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

11BETA-HYDROXYTESTOSTERONE Usage And Synthesis

Uses

11BETA-hydroxytestosterone may be used as a drug in human or animal subjects for the prevention or reversal of mitochondrial damage, for the treatment or prevention of diseases related to mitochondrial dysfunction or depletion, and for inducing mitochondrial regeneration or remodeling as a means of treating diseases related to mitochondrial structural and functional abnormalities.

Description

11β-hydroxy Testosterone is a metabolite of testosterone.1 It is formed from testosterone primarily by the cytochrome P450 (CYP) isoform CYP3A4.WARNING This product is not for human or veterinary use.

Definition

ChEBI: 11beta-hydroxytestosterone is an androstanoid that is testosterone carrying an additional hydroxy substituent at the 11beta-position. It has a role as a bacterial xenobiotic metabolite, a human xenobiotic metabolite and a marine metabolite. It is a 17beta-hydroxy steroid, a 3-oxo-Delta(4) steroid, an androstanoid, a C19-steroid and an 11beta-hydroxy steroid. It is functionally related to a testosterone.

References

[1] MAN HO CHOI. Characterization of testosterone 11 beta-hydroxylation catalyzed by human liver microsomal cytochromes P450.[J]. Drug Metabolism and Disposition, 2005, 33 6: 714-718. DOI: 10.1124/dmd.104.003327

11BETA-HYDROXYTESTOSTERONE(1816-85-9)Related Product Information

• (2E)-N-(2-Methylphenyl)-2-butenamide
• Benzoic acid, 4-(bromomethyl)-2-ethoxy-, ethyl ester
• Brivudine Impurity 5
• tenonitrozole
• (3,4-Dihydroxyphenyl)(4-Methylphenyl)Methanone
• 16-BETA-HYDROXYTESTOSTERONE
• Voriconazole Impurity 32
• 1-(Oxetan-3-yl)-1H-pyrazole-4-carboxylic acid
• DL-Menthol
• 3-METHYLCYCLOPENTANOL
• (+)-NEOMENTHOL
• Rhodinol
• (+/-)-NEOMENTHOL
• 1-CYCLOHEXYL-1-PROPANOL
• 7-ETHYL-2-METHYL-4-UNDECANOL
• 3,3-DIMETHYL-1-BUTANOL
• 3,7-DIMETHYL-1-OCTANOL
• 3,4-DIMETHYLCYCLOHEXANOL