alpiropride Chemical Properties

Melting point:

168.5-169°

Density 

1.227±0.06 g/cm3(Predicted)

pka

11?+-.0.50(Predicted)

Safety Information

Toxicity

LD50 in male mice (mg/kg): 44 i.v.; 184 i.p.; 204 s.c.; 3600 orally (Perrot, Thominet, 1985)

alpiropride Usage And Synthesis

Description

Alpiropride is a sulpiride-like dopamine antagonist reportedly useful in the treatment of migraine. Among the various sulpiride analogs, alpiropride has shown the largest separation between affinities for D₂ and D₄ binding sites in the brain.

Originator

Delagrange (France)

Definition

ChEBI: Alpiropride is a sulfonamide and a member of benzenes.

brand name

Rivestel

alpiropride(81982-32-3)Related Product Information

• m-Toluenesulfonamide, alpha-amino- (5CI)
• sulmepride
• alpiropride
• 1-Allyl-2-aminomethylpyrrolidine
• Sulpiride
• 2-amino-5-methylbenzenesulfonamide