AC-93253 IODIDE Chemical Properties

Melting point:

185-188 °C

storage temp. 

2-8°C

solubility 

DMSO: >10mg/mL

form 

solid

color 

dark purple

Safety Information

WGK Germany 

3

AC-93253 IODIDE Usage And Synthesis

Uses

AC-93253 Iodide is a RAR agonist. It is also a SIRT2 and Src inhibitor. It triggers the downregulation of melanoma progression markers and the inhibition of melanoma cell proliferation.

Biological Activity

AC-93253 is a potent, cell permeable, subtype selective RAR (RARα) agonist. EC50 = 6.3 μM. AC-93253 has high selectivity; 89% for RARα vs 67% for RARβ1, 35% for RARβ2, and 11% for RARγ.