DIHYDROCODEINE TRIFLUOROACETATE
DIHYDROCODEINE TRIFLUOROACETATE Basic information
- Product Name:
- DIHYDROCODEINE TRIFLUOROACETATE
- Synonyms:
-
- 4,5-alpha-epoxy-3-methoxy-17-methyl-morphinan-6-alpha-o
- 4,5alpha-Epoxy-3-methoxy-17-methylmorphinan-6alpha-ol
- 6-alpha-hydrocodol
- 6alpha-Hydrocodol
- 6-Hydroxy-3-methoxy-N-methyl-4,5-epoxymorphinan
- 7,8-dihydro-codein
- 7,8-Dihydrocodeine
- 8,14-Dihydroneopine
- CAS:
- 125-28-0
- MF:
- C20H24F3NO4
- MW:
- 399.4
- EINECS:
- 204-732-3
- Mol File:
- 125-28-0.mol
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DIHYDROCODEINE TRIFLUOROACETATE Chemical Properties
- Melting point:
- 112-113°
- Boiling point:
- bp15 248°
- Density
- 1.1412 (rough estimate)
- refractive index
- 1.5740 (estimate)
- Flash point:
- 9℃
- storage temp.
- 2-8°C
- solubility
- DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 10 mg/ml
- form
- A neat solid
- EPA Substance Registry System
- Morphinan-6-ol, 4,5-epoxy-3-methoxy-17-methyl-, (5?,6?)- (125-28-0)
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Safety Information
- Hazard Codes
- F,T
- Risk Statements
- 11-23/24/25-39/23/24/25
- Safety Statements
- 7-16-36/37-45
- RIDADR
- UN1230 - class 3 - PG 2 - Methanol, solution
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DIHYDROCODEINE TRIFLUOROACETATE Usage And Synthesis
Originator
Bicodein,Uquifa
Definition
ChEBI: Dihydrocodeine is a morphinane alkaloid.
Manufacturing Process
The codein was reduced by hydrogen in the presence catalyst Pt (or Pd, or Ni)
and 7,8-dihydrocodein was obtained.
To the 7,8-dihydrocodein tartaric acid was added and mixed, in the result 7,8-
dihydrocodein bitartrate was obtained.
Therapeutic Function
Antitussive, Narcotic analgesic
Safety Profile
Poison by ingestion, intravenous, and subcutaneous routes. Human systemic effects by ingestion and subcutaneous routes: somnolence, miosis (pupillary constriction), and respiratory depression. An analgesic. Can cause drug dependency with repeated doses. When heated to decomposition it emits toxic fumes of NOx. See also CODEINE.