OSU6162hydrochloride
OSU6162hydrochloride Basic information
- Product Name:
- OSU6162hydrochloride
- Synonyms:
-
- PNU-96391
- OSU6162hydrochloride
- (3S)-3-[3-(Methylsulfonyl)phenyl]-1-propylpiperidinehydrochloride
- (S)-(-)-(3-methanesulfonyl-phenyl)-1-propyl-piperidine hydrochloride
- (S,S)-3-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine hydrochloride
- PNU-0096391
- CAS:
- 156907-84-5
- MF:
- C15H23NO2S.ClH
- MW:
- 317.879
- Mol File:
- 156907-84-5.mol
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OSU6162hydrochloride Chemical Properties
- storage temp.
- Store at +4°C
- solubility
- H2O: ≥16mg/mL
- form
- powder
- color
- white to tan
- optical activity
- [α]/D -5 to -7°, c = 1 in methanol
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OSU6162hydrochloride Usage And Synthesis
Uses
OSU 6162 Hydrochloride is a weak dopamine D2 receptor antagonist. It is a salt analogue of (-)-OSU (O006162).
Biological Activity
Dopamine stabilizer that lacks high in vitro affinity for various neuroreceptors (K i values are 447 and 1305 nM for D 2 and D 3 receptors respectively and > 1 μ M for other targets). In vivo, shows high D 2 receptor occupancy and is highly active on dopamine synthesis and turnover. Induces stabilizing effects on psychomotor function in behavioral tests without inducing hypolocomotion or catalepsy.
storage
Store at +4°C
OSU6162hydrochlorideSupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
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- 821-50328103-801 18930552037
- 3bsc@sina.com
BOC Sciences
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- 1-631-485-4226; 16314854226
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EMMX Biotechnology LLC
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- 888-539-0666
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TargetMol Chemicals Inc.
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- +1-781-999-5354 +1-00000000000
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Energy Chemical
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- 021-58432009 400-005-6266
- marketing1@energy-chemical.com