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ChemicalBook >  Product Catalog >  Organic Chemistry >  Amides >  Acyclic polyamines and their derivatives >  2,6-Dioxopiperidine-3-ammonium chloride

2,6-Dioxopiperidine-3-ammonium chloride

Basic information Description Safety Supplier Related

2,6-Dioxopiperidine-3-ammonium chloride Basic information

Product Name:
2,6-Dioxopiperidine-3-ammonium chloride
Synonyms:
  • 2,6-Dioxopiperidine-3-ammonium chloride
  • 2,6-Dioxopiperidine-3-ammonium
  • Lenalidomide Impurity 6 HCl
  • Pomalidomide/lenalidomide INT II
  • 3-Amino-piperidine-2,6-dione [2353-44-8] at 262 USD, please be noted, what we provide is HCl salt form
  • 2,6-dioxopiperidin-3-aminium chloride
  • Pomalidomide Impurity 6
  • 6-piperidinedione hydrochloride
CAS:
24666-56-6
MF:
C5H9ClN2O2
MW:
164.59016
EINECS:
807-866-6
Product Categories:
  • Pyrrolidines
  • 24666-56-6
Mol File:
24666-56-6.mol
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2,6-Dioxopiperidine-3-ammonium chloride Chemical Properties

Melting point:
120 °C (approx)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly, Heated), Methanol (Sparingly, Sonicated)
form 
powder
color 
White
InChI
InChI=1S/C5H8N2O2.ClH/c6-3-1-2-4(8)7-5(3)9;/h3H,1-2,6H2,(H,7,8,9);1H
InChIKey
YCPULGHBTPQLRH-UHFFFAOYSA-N
SMILES
C1CC(N)C(=O)NC1=O.Cl
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Safety Information

Risk Statements 
20/21/22
Safety Statements 
3/9-36/37
HS Code 
29339900
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2,6-Dioxopiperidine-3-ammonium chloride Usage And Synthesis

Description

2,6-Dioxopiperidine-3-ammonium chloride is a reagent for preparing lenalidomide that can induce ubiquitination and degradation of CK1α in del (5q) MDS. It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation. Moreover, it is also a metabolite of thalidomide (T338850) that inhibits FGF-induced angiogenesis.

Chemical Properties

White crystal

Uses

2,6-Dioxopiperidine-3-ammonium chloride can be used as an important intermediate of antineoplastic drug lenalidomide.

2,6-Dioxopiperidine-3-ammonium chlorideSupplier

Fuxin Kaituo Fine Chemical Technology Co., Ltd Gold
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15714082442
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Beijing FaMu RuiSi Pharmaceuticals Co.,Ltd Gold
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Jinan Kaypharm Chemical Co.,Ltd. Gold
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0531-86986780 13153183025
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Beijing Hope International Pharmaceutical Technology Development Co., Ltd Gold
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010-010-010-67886402 15600038801
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BeiJing TOP Science Bio-Technology Co., Ltd. Gold
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+86-13439059536 +86-15201677815