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Methyl p-nitrophenylacetate

Basic information Appearance Safety Supplier Related

Methyl p-nitrophenylacetate Basic information

Product Name:
Methyl p-nitrophenylacetate
Synonyms:
  • (4-Nitrophenyl)acetic acid methyl ester
  • 2-(p-Nitrophenyl)acetic acid methyl ester
  • 4-Nitrobenzeneacetic acid methyl ester
  • 4-Nitrophenylacetic acid methyl ester
  • Methyl 2-(4-nitrophenyl)acetate
  • Methyl 2-(4-nitrophenyl)
  • Benzeneacetic acid, 4-nitro-, methyl ester
  • Methyl p-nitrophenylacetate
CAS:
2945-08-6
MF:
C9H9NO4
MW:
195.17
Mol File:
2945-08-6.mol
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Methyl p-nitrophenylacetate Chemical Properties

Melting point:
52.4-53.3 °C
Boiling point:
308.6±17.0 °C(Predicted)
Density 
1.266±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
solid
color 
Off-white
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Safety Information

HS Code 
2915390090
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Methyl p-nitrophenylacetate Usage And Synthesis

Appearance

a pale orange oil

Synthesis

4-nitrophenylacetic acid(2.00 g, 11 mmol) was added to a clean carousel tube. Dimethyl carbonate (3 mL, 3.21 g, 35.6 mmol) was added, and the reaction was heated at reflux overnight. The brown solution was allowed to cool, and poured in to aqueous sodium bicarbonate (10%, 10 mL) while stirring. The resulting mixture was extracted with ethyl acetate (3 x 10 mL). The combined organic layers were washed with water and brine (10 mL each), and dried over anhydrous magnesium sulphate. After filtration and evaporation of the solvents, proton NMR analysis showed the product had formed, and none of the precursor acid remained. No further purification was performed. This gave methyl p-nitrophenylacetate as a pale orange oil (1.929 g, 9.89 mmol, 90%)): 1H NMR (400 MHz, CDCl 3 ) |? 8.20 (d, J = 8.6 Hz, 2H), 7.46 (d, J = 8.6 Hz, 2H, 3.74 (s, 2H), 3.73 (s, 3H).

Methyl p-nitrophenylacetateSupplier

Bide Pharmatech Ltd.
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400-1647117 15221909166
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product02@bidepharm.com
Mashilabs (Shanghai) Co.,Ltd.
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021-00000000 19916721580
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info@mashilabs.com
Changzhou Anxuan Chemical, Co., Ltd.
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0519-89882561 13912302692
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info@anxuanchem.com
Zhengzhou Alfachem Co., Ltd.
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0371-53765687 18937137882
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Yancheng KangdiSen Pharmaceutical Co., Ltd.
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13812573443
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tongbenwan22@163.com