AIDS029690
AIDS029690 Basic information
- Product Name:
- AIDS029690
- Synonyms:
-
- AIDS029690
- 1H,3H-Pyrrolo[1,2-C]thiazole-7-carboxamide, 3-(3-pyridinyl)-, (3R)-
- Acopafant
- Rp 55778
- UNII-H1T03Z1G60
- CAS:
- 125372-33-0
- MF:
- C12H11N3OS
- MW:
- 245.3
- Mol File:
- 125372-33-0.mol
More
Less
AIDS029690 Chemical Properties
- Boiling point:
- 516.4±50.0 °C(Predicted)
- Density
- 1.49±0.1 g/cm3(Predicted)
- pka
- 16.43±0.40(Predicted)
More
Less
AIDS029690 Usage And Synthesis
Uses
Acopafant (Dacopafant; RP 55778) is a potent platelet-activating factor antagonist. Acopafant inhibits the induction of human immunodeficiency virus (HIV) expression in chronically infected cells. Acopafant has the potential for the research of HIV infection[1].
References
[1] Weissman D, . A platelet-activating factor antagonist, RP 55778, inhibits cytokine-dependent induction of human immunodeficiency virus expression in chronically infected promonocytic cells. Proc Natl Acad Sci U S A. 1993 Mar 15;90(6):2537-41. DOI:10.1073/pnas.90.6.2537