VAPREOTIDE ACETATE
VAPREOTIDE ACETATE Basic information
- Product Name:
- VAPREOTIDE ACETATE
- Synonyms:
-
- VAPREOTIDE ACETATE
- Vapreotide (RC160) acetate
- Vapreotide acetate (1:x)
- BMY 41606 acetate
- BMY41606 acetate
- BMY-41606 acetate
- RC 160 acetate
- RC160 acetate
- CAS:
- 849479-74-9
- MF:
- C59H74N12O11S2
- MW:
- 1191.43
- Mol File:
- 849479-74-9.mol
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VAPREOTIDE ACETATE Chemical Properties
- Melting point:
- 176-180°C
- storage temp.
- Hygroscopic, Refrigerator, under inert atmosphere
- solubility
- Acetic Acid (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- Sequence
- {d-Phe}-Cys-Tyr-{d-Trp}-Lys-Val-Cys-Trp-NH2 (Disulfide bridge: Cys2-Cys7)
- Stability:
- Hygroscopic
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VAPREOTIDE ACETATE Usage And Synthesis
Chemical Properties
White Solid
Uses
Vapreotide Acetate is a synthetic somatostatin (S676750) analog predominately used for the treatment of acute variceal bleeding.
in vivo
In cirrhosis, bleeding by rupture of oesophagogastric varices is a severe complication of portal hypertension. The acute administration of vapreotide to rats decreases collateral circulation blood flow while chronic administration attenuated its development[4]. Tumor volumes and weights are reduced by about 40% by RC-160 by s.c. injections at doses of 100 μg/day/animal. Vapreotide can inhibit the growth of androgen-independent prostate cancer when the therapy is started at an early stage of tumor development[5].
IC 50
NK1
VAPREOTIDE ACETATESupplier
Chemsky（shanghai）International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
Cellmano Biotech Limited
- Tel
- 0551-65326643 18156095617
- info@cellmano.com
MedChemexpress LLC
- Tel
- 021-58955995
- sales@medchemexpress.cn
Bide Pharmatech Ltd.
- Tel
- 400-164-7117 13681763483
- product02@bidepharm.com
Wuxi Zhongkun Biochemical Technology Co., Ltd.
- Tel
- 0510-85629785 18013409632
- sales@reading-chemicals.com