RA 642
RA 642 Basic information
- Product Name:
- RA 642
- Synonyms:
-
- RA 642
- 2,2'-[4,8-Bis(diethylamino)pyrimido[5,4-d]pyrimidine-2,6-diyl]bis[(2-methoxyethyl)imino]bisethanol
- RA-642BS
- RXRA-642
- 2-[[4,8-bis(diethylamino)-2-[2-hydroxyethyl(2-methoxyethyl)amino]pyrimido[5,4-d]pyrimidin-6-yl]-(2-methoxyethyl)amino]ethanol
- Ethanol, 2,2'-[[4,8-bis(diethylamino)pyrimido[5,4-d]pyrimidine-2,6-diyl]bis[(2-methoxyethyl)imino]]bis-
- CAS:
- 54093-30-0
- MF:
- C24H44N8O4
- MW:
- 508.66
- Mol File:
- 54093-30-0.mol
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RA 642 Usage And Synthesis
Description
RA 642 is a PDE-inhibitor.
Uses
RA642 is a compound with vasodilatory and hypertensive effects, with the activity of increasing arterial blood pressure, enhancing cerebral blood flow, reducing cerebrovascular resistance and peripheral resistance, and having a papaverine-like relaxant effect on smooth muscle in anesthetized animals.
References
[1] High-performance liquid chromatographic assay for RA 642, a compound with cardiovascular effect, in human and rabbit serum alpha
[2] RA 642, a pyrimido-pyrimidine-derivative with vasodilating and hypertensive potency