SK&F 95601 Chemical Properties

Boiling point:

686.9±65.0 °C(Predicted)

Density 

1.52±0.1 g/cm3(Predicted)

pka

8.70±0.10(Predicted)

SK&F 95601 Usage And Synthesis

Description

SK&F-95601 is a proton pump inhibitor potentially for treatment of gastric ulcer.

Uses

SKF 95601 is a modulator of small conductive Ca2+-activated K+ channels with anti-atrial fibrillation (AF) activity. SKF 95601 may play a role in inhibiting atrial fibrillation by affecting the interaction between intracellular Ca2+ concentration and membrane potential. SKF 95601 has become a potential inhibitory target against atrial fibrillation due to its significant expression in various species, especially human atria[1].

References

[1] Modulation of SK Channels: Insight Into Therapeutics of Atrial Fibrillation DOI:10.1016/j.hlc.2021.01.009