bremazocine
bremazocine Basic information
- Product Name:
- bremazocine
- Synonyms:
-
- [2R,(-)]-6-Ethyl-1,2,3,4,5,6-hexahydro-3-[(1-hydroxycyclopropyl)methyl]-11,11-dimethyl-2,6-methano-3-benzazocin-8-ol
- 2-(1-Hydroxy-cyclopropylmethyl)-5-ethyl-9,9-dimethyl-2'-hydroxy-6,7-benzomorphan
- 2,6-Methano-3-benzazocin-8-ol, 6-ethyl-1,2,3,4,5,6-hexahydro-3-((1-hydroxycyclopropyl)methyl)-11,11-dimethyl-, (2R)-
- 2,6-Methano-3-benzazocin-8-ol, 6-ethyl-1,2,3,4,5,6-hexahydro-3-[(1-hydroxycyclopropyl)methyl]-11,11-dimethyl-, (2R,6S)-
- CAS:
- 75684-07-0
- MF:
- C20H29NO2
- MW:
- 315.45
- Mol File:
- 75684-07-0.mol
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bremazocine Chemical Properties
- Boiling point:
- 451.2±45.0 °C(Predicted)
- Density
- 1.155±0.06 g/cm3(Predicted)
- pka
- 10.12±0.60(Predicted)
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bremazocine Usage And Synthesis
Description
Bremazocineis a potent, log-acting opiate kappa-agonist & centrally acting analgesic.
Uses
Bremazocine is a potent opioid kappa receptor agonist with analgesic activity. Bremazocine induces peripheral analgesia by releasing endogenous norepinephrine. The analgesic effect of bremazocine is associated with interaction with adenosine receptors. Bremazocine produces a dose-dependent peripheral analgesia after topical application. The effect of bremazocine is affected by nonselective α(2) adrenaline receptor antagonists, suggesting that it acts through a norepinephrine pathway[1].
Definition
ChEBI: Bremazocine is a benzazocine.
References
[1] Mu, delta, and kappa opioid receptor agonists induce peripheral antinociception by activation of endogenous noradrenergic system
bremazocineSupplier
LGM Pharma
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TargetMol Chemicals Inc.
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Nantong QuanYi Biotechnology Co., Ltd
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TargetMol Chemicals Inc.
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TargetMol Chemicals Inc.
- Tel
- +17819995354
- marketing@targetmol.com