YT 146
YT 146 Basic information
- Product Name:
- YT 146
- Synonyms:
-
- YT 146
- 2-(1-Octynyl)adenosine
- YT146|||YT-146
- CAS:
- 90596-75-1
- MW:
- 0
- Mol File:
- 90596-75-1.mol
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YT 146 Usage And Synthesis
Uses
YT 146 is a potent agonist of A2 adenosine receptor (A2 AR) agonist. YT 146 causes a concentreation dependent cAMP accumulation, with the EC50 of 1.5 nM. YT 146 has cardioprotective effects[1].
IC 50
A2AR
References
[1] Jun Sasamori, et al. Cardioprotective effects of 2-octynyladenosine (YT-146) in ischemic/reperfused rat hearts. J Cardiovasc Pharmacol. 2011 Feb;57(2):166-73. DOI:10.1097/FJC.0b013e318201c264
YT 146Supplier
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