pachysamine A
pachysamine A Basic information
- Product Name:
- pachysamine A
- Synonyms:
-
- pachysamine A
- (20S)-N,N',N'-Trimethyl-5α-pregnane-3α,20-diamine
- Pregnane-3,20-diamine, N3,N20,N20-trimethyl-, (3α,5α,20S)-
- CAS:
- 6801-29-2
- MF:
- C24H44N2
- MW:
- 360.62
- Mol File:
- 6801-29-2.mol
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pachysamine A Chemical Properties
- Melting point:
- 167-8°C
- Boiling point:
- 433.3±18.0 °C(Predicted)
- Density
- 0.98±0.1 g/cm3(Predicted)
- pka
- 10.69±0.70(Predicted)
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pachysamine A Usage And Synthesis
Description
A pregnane alkaloid isolated from Pachysandra terminalis Sieb. et 'Zucc., the base crystallizes in colourless prisms from EtOH and is optically active with [α]10D + 20° (CHC13). The N-acety1 derivative has m.p. 150-2°C and the N_x0002_methyl compound, m.p. 165.5-167°C; [α]10D + 16° (CHCI3). The structure has been elucidated by chemical and spectroscopic methods and is 20adimethy1amino-3a-methylamino-5a-pregnane.
References
Tomita, Uyeo, Kikuchi., Tetrahedron Lett., 1641 (1964)