Lu 2443
Lu 2443 Basic information
- Product Name:
- Lu 2443
- Synonyms:
-
- Lu 2443
- 4,5-Dihydro-3-methyl-2-phenyl-5-thiolato-1,3,4-thiadiazol-3-ium
- CAS:
- 19703-86-7
- MF:
- C9H8N2S2
- MW:
- 208.30322
- Mol File:
- 19703-86-7.mol
More
Less
Lu 2443 Chemical Properties
- Melting point:
- 221 °C
More
Less
Lu 2443 Usage And Synthesis
Description
Lu 2443 is an antiepileptic mesoionic.
Uses
LU 2443 is an orally active antiepileptic mesoionic. LU 2443 is extensively absorbed, in the maximum 18% are eliminated unabsorbed in rats. The half-time of the activity in plasma is 13.17 h[1].
References
[1] Neidlein R, et al. Biotransformation und Pharmakokinetik von mesoionischem Didehydro-4-methyl-5-phenyl-1,3,4-thiadiazolidin-2-thion (LU 2443). Untersuchungen zur Pharmakokinetik an Ratten [Biotransformation and pharmacokinetics of mesionic didehydro-4-methyl-5-phenyl-1,3,4-thiadiazolidine-2-thione (LU 2443). Studies on the pharmacokinetics in rats]. Arzneimittelforschung. 1982;32(11):1447-52. PMID:6891252