altertoxin I Chemical Properties

Boiling point:

699.8±55.0 °C(Predicted)

Density 

1.694±0.06 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

Dichloromethane: 10 mg/ml

form 

A powder

pka

7.54±0.60(Predicted)

biological source

rabbit

Safety Information

RIDADR 

3172

HazardClass 

6.1(b)

PackingGroup 

III

altertoxin I Usage And Synthesis

Uses

Altertoxin I (Dihydroalterperylenol) is a quinone-type mycotoxin produced by Alternaria alternata fungi, which is mutagenic and cytotoxic, and can weakly disrupts metabolic communication[1].

References

[1] Jarolim K, et al. Activation of the Nrf2-ARE pathway by the Alternaria alternata mycotoxins altertoxin I and II. Arch Toxicol. 2017 Jan;91(1):203-216. DOI:10.1007/s00204-016-1726-7
[2] Boutin BK, et al. Effects of purified altertoxins I, II, and III in the metabolic communication V79 system. J Toxicol Environ Health. 1989;26(1):75-81. DOI:10.1080/15287398909531234
[3] Stack ME, et al. Mutagenicity of the Alternaria metabolites altertoxins I, II, and III. Appl Environ Microbiol. 1986 Oct;52(4):718-22. DOI:10.1128/aem.52.4.718-722.1986

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