LY 219057
LY 219057 Basic information
- Product Name:
- LY 219057
- Synonyms:
-
- LY 219057
- 1-Pyrazolidinecarbothioamide, N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxo-4,5-diphenyl-, (4R,5S)-rel-
- CAS:
- 150351-93-2
- MF:
- C23H17ClF3N3OS
- MW:
- 475.91
- Mol File:
- 150351-93-2.mol
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LY 219057 Chemical Properties
- Density
- 1.430±0.06 g/cm3(Predicted)
- pka
- 10.38±0.60(Predicted)
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LY 219057 Usage And Synthesis
Description
LY 219057 is a potent, competitive, and specific CCK receptor antagonist on the exocrine pancreas.
Uses
LY219057 is a potent antagonist of cholecystokinin octapeptide (CCK-8), with the ID50 of 287.5 nM[1][2].
References
[1] T Akiyama, et al. Characterization of a new diphenylpyrazolidinone cholecystokinin antagonist in vitro isolated rat pancreatic acini. Int J Pancreatol. 1993 Oct;14(2):167-73. DOI:10.1007/BF02786123