3,6-DIBROMOTHIENO[3,2-B]THIOPHENE Chemical Properties

Melting point:

127 °C

Boiling point:

332.4±37.0 °C(Predicted)

Density 

2.209±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

form 

powder to crystal

color 

White to Yellow to Orange

InChI

InChI=1S/C6H2Br2S2/c7-3-1-9-6-4(8)2-10-5(3)6/h1-2H

InChIKey

DFMPVYZMICAYCS-UHFFFAOYSA-N

SMILES

C12C(Br)=CSC=1C(Br)=CS2

Safety Information

HS Code 

2934999090

3,6-DIBROMOTHIENO[3,2-B]THIOPHENE Usage And Synthesis

Uses

3,6-Dibromothiophene[3,2-B]thiophene is used as a pharmaceutical and electronic intermediate.

Application

3,6-Dibromothiophene[3,2-B]thiophene is an organic synthesis intermediate and a pharmaceutical intermediate, mainly used in laboratory research and development and chemical and pharmaceutical synthesis processes.

Synthesis

The general procedure for the synthesis of 3,6-dibromothieno[3,2-b]thiophene from tetrabromothieno[3,2-B]thiophene was carried out as follows: tetrabromothieno[3,2-B]thiophene (9.12 g, 20 mmol), acetic acid (500 ml), and toluene (200 ml) were added to the reactor, followed by zinc powder (2.62 g, 40 mmol). The reaction mixture was filtered and the filtrate was concentrated to give the intermediate 3,6-dibromothieno[3,2-b]thiophene (5.36 g, 90% yield). After completion of the reaction, the synthesis of intermediate C-28-2 was carried out.

References

[1] Patent: CN107056798, 2017, A. Location in patent: Paragraph 0065; 0066; 0067
[2] Patent: WO2016/92065, 2016, A1. Location in patent: Page/Page column 21; 22
[3] Journal of the Chemical Society - Perkin Transactions 1, 1997, # 22, p. 3465 - 3470
[4] Patent: CN103172646, 2016, B. Location in patent: Paragraph 0114-0116
[5] Chemical Communications, 2005, # 9, p. 1161 - 1163

3,6-DIBROMOTHIENO[3,2-B]THIOPHENE(392662-65-6)Related Product Information

• Tetrabromothiophene
• Thiophene
• Dibromothiophene
• Pyrrolo[3,4-c]pyrrole-1,4-dione, 3,6-bis(5-bromo-2-thienyl)-2,5-dihydro-
• 3,6-Di(2-thienyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione
• 3,4-Dimethoxythiophene
• 2,5-Di(HD)-3,6-di(5-broMothiophen)diketopyrrolopyrrole
• 3,6-Bis(5-broMothiophen-2-yl)-2,5-bis(2-octyldodecyl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione
• 3,6-Di(thieno[3,2-b]thiophen-2-yl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione
• 3,6-bis(5-broMo-4-(2-ethylhexyl)thiophen-2-yl)-1,2,4,5-tetrazine
• 3,6-Bis(5-bromo-2-thienyl)-2,5-dihydro-2,5-dioctylpyrrolo[3,4-c]pyrrole-1,4-dione
• 4,4'-Dibutoxy-2,2'-bis(trimethylstannyl)-5,5'-bithiazole
• DPP‐iC12
• 3,4-Dibromothiophene
• 3,6-Bis(5-bromo-2-thienyl)-2,5-bis(2-ethylhexyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione
• TETRABROMO-THIENO[3,2-B]THIOPHENE
• 3,6-DIBROMOTHIENO[3,2-B]THIOPHENE
• 3-BROMOTHIENO[3,2-B]THIOPHENE