3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophene-2-carboxylic acid Chemical Properties

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Solid

color 

Red to Dark Red

Stability:

Light Sensitive

3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophene-2-carboxylic acid Usage And Synthesis

Description

Pyrrothiogatain is a novel inhibitor of GATA family proteins, targeting the DNA-binding activity of GATA3 and other members of the GATA family, inhibiting the interaction between GATA3 and SOX4, significantly suppressing Th2 cell differentiation, without impairing Th1 cell differentiation, and inhibiting the expression and production of Th2 cytokines.

Uses

3-(2,5-Dimethyl-1H-pyrrol-1-yl)-2-thiophenecarboxylic Acid is involved in the regulation of GATA3 DNA binding activity in Th2 cells.