1-[(4-HYDROXYPHENOXY)ETHYLIDENE]BIS[PHOSPHINYLIDYNEBIS(OXYMETHYLENE)]-2,2-DIMETHYLPROPANOATE Chemical Properties

Boiling point:

754.8±60.0 °C(Predicted)

Density 

1.232±0.06 g/cm3(Predicted)

storage temp. 

Store at -80°C

pka

9.55±0.15(Predicted)

1-[(4-HYDROXYPHENOXY)ETHYLIDENE]BIS[PHOSPHINYLIDYNEBIS(OXYMETHYLENE)]-2,2-DIMETHYLPROPANOATE Usage And Synthesis

Uses

L-690,488 is a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330.

Definition

ChEBI: 2,2-dimethylpropanoic acid [[1-[bis[(2,2-dimethyl-1-oxopropoxy)methoxy]phosphoryl]-1-(4-hydroxyphenoxy)ethyl]-[(2,2-dimethyl-1-oxopropoxy)methoxy]phosphoryl]oxymethyl ester is an organooxygen compound and a pivalate ester. It is functionally related to a tetracarboxylic acid.

Biological Activity

Cell-permeable prodrug of the potent inositol monophosphatase inhibitor L-690,330 ([1-(4-Hydroxyphenoxy)ethylidene]bisphosphonic acid ); penetrates cells more effectively than its metabolite.

1-[(4-HYDROXYPHENOXY)ETHYLIDENE]BIS[PHOSPHINYLIDYNEBIS(OXYMETHYLENE)]-2,2-DIMETHYLPROPANOATE(142523-14-6)Related Product Information

• L-690,330
• 1-[(4-HYDROXYPHENOXY)ETHYLIDENE]BIS[PHOSPHINYLIDYNEBIS(OXYMETHYLENE)]-2,2-DIMETHYLPROPANOATE
• Etidronic acid monohydrate