ASPOCHALASIN D
ASPOCHALASIN D Basic information
- Product Name:
- ASPOCHALASIN D
- Synonyms:
-
- ASPOCHALASIN D
- 1H-Cycloundec(d)isoindole-1,15(2H)-dione, 3,3a,4,6a,9,10,11,12-octahyd ro-11,12-dihydroxy-4,5,8-trimethyl-3-(2-methylpropyl)-, (3S,3aR,4S,6aS ,7E,11R,12S,13E,15aS)-
- [3S,13E,17S,18S,19E,(-)]-17,18-Dihydroxy-14-methyl-3-(2-methylpropyl)-10-nor[11]cytochalasa-6,13,19-triene-1,21-dione
- isoaspochalasinC
- CAS:
- 71968-02-0
- MF:
- C24H35NO4
- MW:
- 401.54
- Product Categories:
-
- Antibiotic
- Mol File:
- 71968-02-0.mol
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ASPOCHALASIN D Chemical Properties
- Boiling point:
- 607.6±55.0 °C(Predicted)
- Density
- 1.15±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: soluble
- form
- A solid
- pka
- 13.10±0.70(Predicted)
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ASPOCHALASIN D Usage And Synthesis
Description
Aspochalasin D is a co-metabolite originally isolated from A. microcysticus with aspochalasins A, B, and C, that was initially thought to be inactive. It has antibacterial activity against Gram-positive and Gram-negative bacteria at a concentration of 1 mg/ml. Aspochalasin D is more cytotoxic, via apoptosis, to Ba/F3-V12 cells in an IL-3-free medium than in an IL-3-containing medium (IC50s = 0.49 and 1.9 μg/ml, respectively).
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