Basic information Safety Supplier Related

K-strophanthin-beta

Basic information Safety Supplier Related

K-strophanthin-beta Basic information

Product Name:
K-strophanthin-beta
Synonyms:
  • STROPHANTHIN
  • K-strophanthin-beta
  • 3β-[(4-O-β-D-Glucopyranosyl-3-O-methyl-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-5β-card-20(22)-enolide
  • .beta.-K-Strophanthin
  • .beta.-Strophanthobioside, strophanthidin-3
  • 5.beta.-Card-20(22)-enolide, 3.beta.-[(2,6-dideoxy-4-o-.beta.-D-glucopyranosyl-3-o-methyl-.beta.-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-
  • Card-20(22)-enolide, 3-[(2,6-dideoxy-4-o-.beta.-D-glucopyranosyl-3-o-methyl-.beta.-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-, (3.beta.,5.beta.)-
  • Nsc4320
CAS:
560-53-2
MF:
C36H54O14
MW:
710.81
Mol File:
560-53-2.mol
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K-strophanthin-beta Chemical Properties

Melting point:
195°C
Boiling point:
628.39°C (rough estimate)
Density 
1.1625 (rough estimate)
refractive index 
1.6130 (estimate)
pka
12.89±0.70(Predicted)
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K-strophanthin-beta Usage And Synthesis

Description

Strophanthin is made up of a mixture of glycosides, mainly K-strophanthin- β, 3β,5,14-trihydroxy-10-oxo-5β-card-20(22)-enolide-3-D-cymaro-β-D-glycoside, and K-strophanthoside, 3β,5,14-trihydroxy-10-oxo-5β-card-20(22)-enolide-3-Dcymaro- β-D-gluco-α-D-glycozide. It is isolated primarily from the family Strophantus kombe.

Uses

Strophanthin is used in severe cardiovascular insufficiency, in particular after myocardial infarction, for chronic cardiac insufficiency, cardiac decompensation, supraventricular tachycardia, and ventricular arrhythmia.

Definition

ChEBI: K-Strophanthin-beta is a cardenolide glycoside and a steroid aldehyde.

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