13-Methoxy-14-[(3R)-17-methoxy-17-oxovobasan-3α-yl]ibogamine-18-carboxylic acid methyl ester Chemical Properties

Melting point:

222-225 °C (decomp)

Density 

1.30±0.1 g/cm3(Predicted)

pka

17.01±0.60(Predicted)

13-Methoxy-14-[(3R)-17-methoxy-17-oxovobasan-3α-yl]ibogamine-18-carboxylic acid methyl ester Usage And Synthesis

Uses

Conodurine is a monoterpenoid indole alkaloid. Conodurine can inhibit lysosomal acidification. Conodurineis isolated from the natural Tabernaemontana corymbosa[1].

References

[1] Zhang Y, Ding X, Yuan YX, Guo LL, Hao XJ. Cytotoxic Monoterpenoid Indole Alkaloids from Tabernaemontana corymbosa as Potent Autophagy Inhibitors by the Attenuation of Lysosomal Acidification. J Nat Prod. 2020 May 22;83(5):1432-1439. DOI:10.1021/acs.jnatprod.9b00856

13-Methoxy-14-[(3R)-17-methoxy-17-oxovobasan-3α-yl]ibogamine-18-carboxylic acid methyl ester(2665-57-8)Related Product Information

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• 13-Methoxy-14-[(3R)-17-methoxy-17-oxovobasan-3α-yl]ibogamine-18-carboxylic acid methyl ester