(S)-1-CYCLOHEXYL-4-[4-(2-METHOXY-PHENYL)-PIPERAZIN-1-YL]-2-PHENYL-BUTAN-1-ONE Chemical Properties

Boiling point:

587.8±50.0 °C(Predicted)

Density 

1.082±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

pka

7.17±0.10(Predicted)

Safety Information

HS Code 

2933599590

(S)-1-CYCLOHEXYL-4-[4-(2-METHOXY-PHENYL)-PIPERAZIN-1-YL]-2-PHENYL-BUTAN-1-ONE Usage And Synthesis

Uses

LY426965 is a potent arylpiperazine compound known for its role as a full antagonist of the serotonin 1A receptor, lacking partial agonist activity. It is identified as a selective 5-HT1A antagonist, showing promise in preclinical studies for treating conditions associated with serotonin dysregulation, such as smoking cessation and depression-related disorders[1].

References

[1] Asymmetric Construction of Quaternary Centers by Enantioselective Allylation: Application to the Synthesis of the Serotonin Antagonist LY426965

(S)-1-CYCLOHEXYL-4-[4-(2-METHOXY-PHENYL)-PIPERAZIN-1-YL]-2-PHENYL-BUTAN-1-ONE(228418-82-4)Related Product Information

• 1-CYCLOHEXYL-2-PHENYL-1-ETHANONE
• (S)-1-CYCLOHEXYL-4-[4-(2-METHOXY-PHENYL)-PIPERAZIN-1-YL]-2-PHENYL-BUTAN-1-ONE
• 1-DECYLPIPERAZINE