Basic information Safety Supplier Related

(R)-N-Fmoc-2-(7'-octenyl) alanine

Basic information Safety Supplier Related

(R)-N-Fmoc-2-(7'-octenyl) alanine Basic information

Product Name:
(R)-N-Fmoc-2-(7'-octenyl) alanine
Synonyms:
  • (R)-N-Fmoc-2-(7'-octenyl) alanine
  • (2R)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-9-decenoic acid
  • (R)-N-(9-Fluorenylmethylcarbamate)-2-(2'-octenyl)alanine
  • (R)-N-FMoc-2-(7'-octenyl) alanine, 97%Min
  • (R)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-2-Methyldec-9-enoic acid
  • (R)-N-FMOC-Α-(7-OCTENYL)ALANINE
  • FMoc-α-Me-D-Gly(Octenyl)-OH
  • (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methyldec-9-enoic acid
CAS:
945212-26-0
MF:
C26H31NO4
MW:
421.53
Product Categories:
  • α-Methyl Amino Acids
Mol File:
945212-26-0.mol
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(R)-N-Fmoc-2-(7'-octenyl) alanine Chemical Properties

Boiling point:
588.3±45.0 °C(Predicted)
Density 
1.140
storage temp. 
-20°C
form 
liquid
pka
3.94±0.41(Predicted)
color 
pale yellow
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Safety Information

Hazard Codes 
N
Risk Statements 
50
Safety Statements 
61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
TSCA 
No
HS Code 
2922498590
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(R)-N-Fmoc-2-(7'-octenyl) alanine Usage And Synthesis

Uses

(2R)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-9-decenoic Acid, is a stable antimicrobial peptide, that can be isolated from the venom of wild bee Lasioglossum laticeps.

Uses

Olefinic alpha-methyl amino acid for peptide stapling. Upon incorporation of this amino acid into a peptide, along with another of the same or derivative with a different length of the olefinic side chain, the two can be ′stapled′ via a ring closing metathesis reaction with Grubb′s catalyst (product # 579726). The resulting stapled peptide macrocycle has been shown to stabilize the alpha-helical structure of peptides, which can lead to favorable biological characteristics such as increased proteolytic stability and cellular uptake.

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