1-phenyl-1H-pyrazol-5-ol Chemical Properties

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

InChI

InChI=1S/C9H8N2O/c12-9-6-7-10-11(9)8-4-2-1-3-5-8/h1-7,12H

InChIKey

XODZKIFTJBMDRO-UHFFFAOYSA-N

SMILES

N1(C2=CC=CC=C2)C(O)=CC=N1

1-phenyl-1H-pyrazol-5-ol Usage And Synthesis

Synthesis

To three 100 mL reaction bottles were added 10.8 g (100 mmol) of phenylhydrazine and 11.6 g (100 mmol) of methyl 3-methoxyacrylate, followed by 100 mL of methanol as solvent. The reaction mixture was heated to reflux and kept reacting for about 6 hours. Upon completion of the reaction, the reaction solution was quantitatively analyzed by high performance liquid chromatography (HPLC) and the yield of 1-phenyl-5-hydroxypyrazole was measured to be 85.7%.

References

[1] Patent: CN104059020, 2016, B. Location in patent: Paragraph 0016; 0017

1-phenyl-1H-pyrazol-5-ol(876-93-7)Related Product Information

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