Basic information Safety Supplier Related

Cyclopenin

Basic information Safety Supplier Related

Cyclopenin Basic information

Product Name:
Cyclopenin
Synonyms:
  • )-Isocyclopenin
  • )-Isocyclopenine
  • Spiro[3H-1,4-benzodiazepine-3,2'-oxirane]-2,5(1H,4H)-dione, 4-methyl-3'-phenyl-, (2'R,3'R)-rel-
  • rel-Isocyclopenine
  • Cyclopenin, AChE inhibitor
  • (±)-Cyclopenin
CAS:
19553-26-5
MF:
C17H14N2O3
MW:
294.3
Mol File:
19553-26-5.mol
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Cyclopenin Chemical Properties

Boiling point:
572.5±50.0 °C(Predicted)
Density 
1.40±0.1 g/cm3(Predicted)
pka
12.92±0.40(Predicted)
form 
powder
color 
White to slightly pink
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Cyclopenin Usage And Synthesis

Uses

Cyclopenin is one of an unusual family of benzodiazepine metabolites produced by a number of Penicillium species. Often mistakenly referred to as a mycotoxin, cyclopenin shows little toxicity against mammalian cells, bacteria or fungi in vitro. Cyclopenin is an intermediate in the biosynthesis of 3-O-methyl viridicatin, a strong inhibitor of TNFα-induced replication HIV. Lack of availability has hitherto restricted a more intensive investigation of this interesting metabolite.

Uses

(±)-Isocyclopenine is the racemic form of metabolites of natural product cyclopeptine (C991620) isolated from Penicillium cyclopium. Intermediate in the biosynthesis of the viridicatins.

storage

+4°C

CyclopeninSupplier

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