1-Methyl-3-oxocyclobutane-1-carboxylic acid Chemical Properties

Boiling point:

272.3±33.0 °C(Predicted)

Density 

1.305±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

pka

4.39±0.20(Predicted)

form 

solid

color 

white

Safety Information

HS Code 

2918999090

1-Methyl-3-oxocyclobutane-1-carboxylic acid Usage And Synthesis

Description

1-Methyl-3-oxocyclobutane-1-carboxylic acid is a cyclobutane derivative that inhibits the biosynthesis of melanin. It has been shown to inhibit the enzyme tyrosinase and to decrease the production of melanin in melanoma cells. 1-Methyl-3-oxocyclobutane-1-carboxylic acid is also a potent fungicide, inhibiting the growth of fungi by binding to enzymes in their biosynthetic pathway. This compound has been used as a lead compound for the development of other inhibitors of tyrosinase. 1-Methyl-3-oxocyclobutane-1-carboxylic acid inhibits asparagine, which blocks its interaction with carboxamide, preventing amine formation and subsequent inhibition of protein synthesis.