DCB
DCB Basic information
- Product Name:
- DCB
- Synonyms:
-
- NSC 67224
- [(3-CHLOROPHENYL)METHYLENE]HYDRAZONE-3-CHLOROBENZALDEHYDE
- 3,3'-DICHLOROBENZALDAZINE
- 3,3μ-Dichlorobenzaldazine, NSC 67224
- 1,1'-(Azinobismethylidyne)bis(3-chlorobenzene)
- 1,2-Bis(3-chlorobenzylidene)hydrazine
- 3,3'-Dichlorobenzylideneazine
- α,α'-Azinobis(m-chlorotoluene)
- CAS:
- 6971-97-7
- MF:
- C14H10Cl2N2
- MW:
- 277.15
- Product Categories:
-
- Glutamate receptor
- Mol File:
- 6971-97-7.mol
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DCB Chemical Properties
- Melting point:
- 40 °C
- Boiling point:
- 387.8±42.0 °C(Predicted)
- Density
- 1.21±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: ~6.8 mg/mL
- form
- solid
- pka
- 5.84±0.50(Predicted)
- color
- yellow
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Safety Information
- Hazard Codes
- Xn,N
- Risk Statements
- 22-37/38-41-43-50/53
- Safety Statements
- 26-36/37-60-61
- RIDADR
- UN 3077 9/PG 3
- WGK Germany
- 3
MSDS
- Language:English Provider:SigmaAldrich
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DCB Usage And Synthesis
Uses
DCB is an allosteric ligand for mGluR-5 (1). Regulates glutamate concentration however may induce neuronal damage through cerebral ischemia (2).
Biological Activity
Allosteric ligand for the metabotropic glutamate receptor mGlu 5 ; displays neutral modulation. Does not affect agonist-stimulated mGlu 5 responses, but blocks regulation of the receptor by other allosteric modulators such as DFB ([(3-Fluorophenyl)methylene]hydrazone-3-fluorobenzaldehyde ) and DMeOB ([(3-Methoxyphenyl)methylene]hydrazone-3-methoxybenzaldehyde ).
DCBSupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
BOC Sciences
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- 1-631-485-4226; 16314854226
- info@bocsci.com
EMMX Biotechnology LLC
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- 888-539-0666
- info@emmx.com
MQ (shanghai) Pharmaceuticals Co., Ltd.
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- 13761635123
- 1014988033@qq.com
TargetMol Chemicals Inc.
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- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com