DL-GOITRIN Chemical Properties

Melting point:

50°

alpha 

D31 -70.5° (c = 2 in methanol)

storage temp. 

2-8°C

solubility 

DMSO: 2mg/mL, clear

pka

10.5(at 25℃)

form 

powder

color 

white to beige

optical activity

[α]/D 85 to 67° (C=1.0g/100mL, CDCl3 )

Safety Information

Hazardous Substances Data

500-12-9(Hazardous Substances Data)

MSDS

• Language:English Provider:ALFA

DL-GOITRIN Usage And Synthesis

Uses

DL-Goitrin is a sulfur-containing oxazolidine, a cyclic thiocarbamate, that reduces the production of thyroid hormones such as thyroxine.

Definition

ChEBI: (S)-goitrin is a 5-ethenyl-1,3-oxazolidine-2-thione that has S-configuration. It is a constituent of a traditional Chinese herbal medicine, Radix isatidis. It has a role as an antiviral agent, a plant metabolite and an antithyroid drug. It is an enantiomer of a (R)-goitrin.

Biological Activity

Goitrin is a sulfur containing alkaloid isolated from Isatis indigotica (Ban Lan Gen) and Brassica vegetables (yellow turnip, broccoli) th at exhibits antiviral, anticancer, and antithyroid activities. Epigoitrin and goitrin appear to show virucidal effect on influenza virus A (H1N1) in vitro and in ovo.

DL-GOITRIN(500-12-9)Related Product Information

• DL-GOITRIN