8-Chloro-arabinoadenosine Chemical Properties

Boiling point:

707.4±70.0 °C(Predicted)

Density 

2.19±0.1 g/cm3(Predicted)

pka

12.90±0.70(Predicted)

8-Chloro-arabinoadenosine Usage And Synthesis

Uses

8-Chloro-arabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005