CYM 2503
CYM 2503 Basic information
- Product Name:
- CYM 2503
- Synonyms:
-
- (9H-FLUOREN-9-YL)METHYL((S)-1(((S)-6(TERTBUTOXYCARBONYL) AMINO-1-((4-METHYL-2-OXO-1,2-DIHYDROQUINOLIN-7-YL)AMINO)-1-OXOHEXAN-2-YL)AMINO))-3-CYCLOHEXYL-1-OXOPROPAN-2-YL) CARBAMATE
- CYM 2503
- L-Lysinamide, 3-cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(1,2-dihydro-4-methyl-2-oxo-7-quinolinyl)-N6-[(1,1-dimethylethoxy)carbonyl]-
- Neuropeptide Y Receptor,electrographic seizure,NPY receptor,CYM 2503,seizure,inhibit,CYM2503,Inhibitor,epilepsy,GalR2,CYM-2503
- tert-butyl N-[(5S)-5-[(2S)-3-cyclohexyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]-5-[(4-methyl-2-oxo-1,2-dihydroquinolin-7-yl)carbamoyl]pentyl]carbamate
- CAS:
- 1308833-36-4
- MF:
- C45H55N5O7
- MW:
- 777.95
- Mol File:
- 1308833-36-4.mol
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CYM 2503 Chemical Properties
- Boiling point:
- 1009.4±65.0 °C(Predicted)
- Density
- 1.210±0.06 g/cm3(Predicted)
- pka
- 10.68±0.46(Predicted)
- form
- A solid
- color
- Off-white to light yellow
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CYM 2503 Usage And Synthesis
Uses
CYM2503 is a putative GalR2-positive allosteric modulator. CYM2503 increases the latency to first electrographic seizure and decreases the total time in seizure. CYM2503 also attenuates electroshock-induced seizures in mice. Galanin receptors type 1 (GalR1) and/or type 2 (GalR2) represent unique pharmacological targets for the research of seizures and epilepsy[1].
References
[1] Lu X, et al. GalR2-positive allosteric modulator exhibits anticonvulsant effects in animal models. Proc Natl Acad Sci U S A. 2010;107(34):15229-15234. DOI:10.1073/pnas.1008986107
CYM 2503Supplier
Shanghai Lollane Biological Technology Co.,Ltd.
- Tel
- 021-52996696,15000506266 15000506266
Shanghai EFE Biological Technology Co., Ltd.
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- 021-65675885 18964387627
- info@efebio.com
ShangHai Biochempartner Co.,Ltd
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- 177-54423994 17754423994
- 2853530910@QQ.com
Jinan Yaoyan Pharmaceutical Co., Ltd.
- Tel
- jnyaoyan@163.com
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
- Tel
- meitaochem@126.com
- meitaochem@126.com