Z-VEID-AFC Chemical Properties

Boiling point:

1087.7±65.0 °C(Predicted)

Density 

1.380±0.06 g/cm3(Predicted)

storage temp. 

−20°C

solubility 

DMSO/DMF: 20 mM

form 

powder

pka

4.09±0.10(Predicted)

Sequence

{Z}-Val-Glu-Ile-Asp-{AFC}

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

Z-VEID-AFC Usage And Synthesis

Uses

Z-VEID-AFC is a fluorescent substrate for caspase-6[1].

Biological Activity

Cell permeable: no', 'Primary Target
A fluorogenic substrate for caspase-6 (Mch2', 'Product does not compete with ATP.', 'Reversible: no

References

[1] Vikas Kaushal, et al. ?Inflammasome-mediated activation of caspase-1 and caspase-6 in primary human neurons.Volume8,?Issue4S_Part_8.Alzheimer 's Association International Conference 2012.

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