FmocNH-PEG3-CH2CH2NH2 HCl
FmocNH-PEG3-CH2CH2NH2 HCl Basic information
- Product Name:
- FmocNH-PEG3-CH2CH2NH2 HCl
- Synonyms:
-
- FmocNH-PEG3-CH2CH2NH2 HCl
- FmocNH-PEG3-CH2CH2NH2 hydrochloride
- Fmoc-PEG3-amine(HCl salt)
- FmocNH-PEG3-CH2CH2NH2 HCl/5,8,11-Trioxa-2-azatridecanoic acid, 13-amino-, 9H-fluoren-9-ylmethyl ester, HCl
- (9H-Fluoren-9-yl)methyl (2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)carbamate hydrochloride
- Fmoc-NH-PEG3-amine Hydrochloride
- CAS:
- 906079-91-2
- MF:
- C23H31ClN2O5
- MW:
- 450.96
- Mol File:
- 906079-91-2.mol
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FmocNH-PEG3-CH2CH2NH2 HCl Chemical Properties
- storage temp.
- -20°C, sealed storage, away from moisture
- form
- Solid
- color
- White to off-white
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FmocNH-PEG3-CH2CH2NH2 HCl Usage And Synthesis
Uses
FmocNH-PEG3-CH2CH2NH2 (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biological Activity
FmocNH-PEG3-CH2CH2NH2 (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50
PEGs
References
[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
FmocNH-PEG3-CH2CH2NH2 HClSupplier
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